Products
API Intermediates
Process Development
Scope
- Process Designing : Route scouting based on literature.
- Process Development : Totally based on cost and scale up size.
- Optimization : Based on minimum effluent and less toxic solvents.
Includes
- Research and development
- Process design based on R & D
- Scale-up at Pilot plant
- Optimization for max. efficiency, minimum
waste and reduction in cost - Commercialization
To create
- Safe process
- Efficient process
- Cost-effective
Lapatinib Intermediate
Crisaborole Intermediate
Hydantoin Epoxy Resin
DMDM Hydantoin
Lapatinib
Citicoline Key Starting Material
Etravirine Intermediate
Citicoline
Lapatinib Intermediate
Teriflunomide
Crisaborole
Sorafenib
Molindone
Hydantoin Epoxy Resin
DMDM Hydantoin
Etravirine Intermediate
Impurity Profiling & Synthesis
Drug Substance and Product
Scope
- Synthesis of Impurities provided in Monograph
- Synthesis of Impurities observed in Forced Degradation and Stability study.
- Synthesis of N-nitroso impurities and N-nitroso of Drug substance
N-Nitroso DimethylAmine NDMA
N-Nitroso DiethylAmine NDEA
N-Nitroso EthylIsopropylAmine NEIPA
N-Nitroso DiIsopropylAmine NDIPA
N-Nitroso DiPropylAmine NDPA
N-Nitroso Di-N-butylAmine NDBA
Torsemide Impurities
Drug Substance and Product unknown impurity
Scope
- Unknown Impurity identification, Synthesis and possible root cause of generation and control in process.
Building Blocks
Skeleton-based
- Pyridine based
- Pyrimidine based
- Boronic acid based
- Boronic ester based
- Oxazole based
- Isoxazole based
- Thiazole based
Skeleton Based - Scope
Aryl/Heteroaryl Boronic ester (pinacolato/Glycolato based)
Alpha carbon thio-alkylation based
Aryl/Heteroaryl Boronic acid based
Wittig Reaction based
Oxazole based
Oxadiazole based
Isoxazole based
Thiodiazole
Aliphatic Building blocks
Thioether-based
α, β-unsaturated based
Sulfone based
Homologue base
Boronic ester based Building blocks
Pinacolato based
Glycolato based
Heterocyclic Building Blocks in CROs/Drug Discovery
Oxadiazole derivatives
Iso-oxazole derivatives
Oxadiazole derivatives
Thiodiazole derivatives
Imidazolyl derivatives
Carbohydrate Based - Scope
Glucose derivatives
Glucuronic acid
Skeleton-based
Skeleton-based
- Pyridine based
- Pyrimidine based
- Boronic acid based
- Boronic ester based
- Oxazole based
- Isoxazole based
- Thiazole based
Skeleton Based - Scope
Aryl/Heteroaryl Boronic ester (pinacolato/Glycolato based)
Alpha carbon thio-alkylation based
Aryl/Heteroaryl Boronic acid based
Wittig Reaction based
Oxazole based
Oxadiazole based
Isoxazole based